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Symbol
Name
ID

Men1
multiple endocrine neoplasia 1
MGI:1316736

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes

Anorexia

Pancreatic islet cell adenoma

Insulinoma

Intestinal carcinoid

Elevated circulating growth hormone concentration

Increased circulating prolactin concentration

Pituitary adenoma

Pituitary corticotropic cell adenoma

Pituitary gonadotropic cell adenoma

Pituitary growth hormone cell adenoma

Pituitary null cell adenoma

Pituitary prolactin cell adenoma

Pituitary thyrotropic cell adenoma

Carcinoid tumor

Pulmonary carcinoid tumor

Pancreatic endocrine tumor

Glucagonoma

Pheochromocytoma

Ependymoma

Cranial nerve compression

Meningioma

Depression

Lethargy

Confusion

Short attention span

Coma

Decreased vigilance

Headache

Atypical absence status epilepticus

Disease(s) Associated with MEN1

multiple endocrine neoplasia type 1

pancreatic cancer

Mouse Phenotypes		abnormal neural tube closure	abnormal pituitary gland morphology	enlarged pituitary gland	increased pituitary gland tumor incidence	increased pituitary adenohypophysis tumor incidence	increased prolactinoma incidence	increased pituitary adenoma incidence	exencephaly
Availability	Mouse Genotype	abnormal neural tube closure	abnormal pituitary gland morphology	enlarged pituitary gland	increased pituitary gland tumor incidence	increased pituitary adenohypophysis tumor incidence	increased prolactinoma incidence	increased pituitary adenoma incidence	exencephaly
	Men1^tm1.1Zqw/Men1^tm1.1Zqw
	Men1^tm1Zqw/Men1^tm1Zqw
	Men1^tm1.1Ctre/Men1⁺
	Men1^tm1.1Gfk/Men1⁺
	Men1^tm1Ctre/Men1⁺
	Men1^tm1Rvt/Men1⁺
	Men1^tm1Zqw/Men1⁺
	Men1^tm2.1Gfk/Men1⁺
	Men1^tm1Gfk/Men1^tm1Gfk Tg(Ins2-cre)25Mgn/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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